The singer has launched the Barbra Streisand Women's Cardiovascular Research and Education Program, which will fund research and education at the famous hospital.
Streisand is one of the best-selling music artists of all time, with more than 68.
For another shot inside the new issue, she could be seen sporting thigh-high boots, a cream trench coat and a floppy hat.
The centerfold featured a nude photograph of Monroe, taken when she was a struggling actress.
Herewith, an exclusive selection of images from the book, many of which have never been published, that capture Streisand like never before.
And they have always been treated with suspicion.