Setting goals is a scientifically proven way to help you stay more focused and become more successful.
Callie and talk about how it doesn't seem real when approaches Callie and tells her that it will be too hard for her to decide what happens to George's organs and because in God's eyes Callie is still George's wife then Callie should decide, Callie accepts.
When Callie told Mark she tried to keep him away from her, Mark told her he'd torture George to make her feel better.